U-bent Fiber optic sensors through precise
geometrical modifications offer high refractive index
sensing, and exceptional evanescent wave
absorbance sensitivity.
U-bent Fiber Optic Sensor
U-shaped fiber optic probes maximize light interaction with sample through efficient evanescent power coupling by virtue of optimized probe geometric design.
U-FOS have high surface sensitivity and zero bulk sensitivity. Hence analytes in complex sample matrices can be analysed without worrying about cross-sensitivity and interference from the matrix.
Remarkable Refractive Index (RI) Sensitivity for Process monitoring
Exceptional Evanescent Wave Absorbance (EWA) Sensitivity for biomolecular assays
Novel characterization tool for in situ nanomaterial synthesis
Real-time monitoring with broad dynamic range for a wide concentration range
Disposable probe cartridges akin to screen-printed electrodes for electrochemical sensors
Dip-type optical probes with small form-factor compatible with PCR tubes
Various surface functionalization protocols have been optimized for silica and polymer U-FOS. Further optimization has been achieved for maximizing immobilization of proteins, nucleic acids, small molecules, or metal organic frameworks to achieve efficient and highly sensitive detection of various chemical and biomarkers.
U-FOS technology can be used for specific detection of proteins, nucleic acids, and small molecules through various labelled & label-free assays (direct, sandwich and competitive).
You can use these probes for any analyte or assay of interest. These probes have been reported to be useful for various disease diagnosis (e.g. pre-eclampsia [1], Covid [2], Tuberclosis [3], endotoxins [4], etc.)
[1] doi.org/10.1016/j.bios.2024.116312
[2] doi.org/10.1109/LSENS.2023.3340598
doi.org/10.1109/JSEN.2021.3107736
[3] doi.org/10.1016/j.bios.2020.112488
[4] doi.org/10.1016/j.bios.2018.12.045